Agents that block this step can function as new antivirulents. Bacteria use proteins called lectins to adhere to the host.My research group will use the following approaches to study bacterial adhesion and communication systems with the long-term objective of using synthetic chemistry to inhibit microbial biofilm formation and decrease virulence. Initial bacterial adhesion to host cells and aggregation is dependent on protein-carbohydrate interactions. During the process of biofilm formation, bacteria capitalize on specific interactions with other bacteria and their host. quorum sensing) that can lead to biofilm formation. Bacteria communicate by secreting small molecule signals that trigger changes in gene expression (e.g. Antibiotic resistance and pathogenic bacterial biofilms are detrimental to human health. My research is situated at the interface of organic chemistry and chemical biology. Outside of work, I enjoy traveling, exploring outside, reading, and watching sports. I joined the faculty at UNCA in 2019 and am excited to be back at a liberal arts school with the opportunity to teach chemistry and biochemistry and lead students in research. I then started postdoctoral research with Professor Laura Kiessling at University of Wisconsin – Madison and then Massachusetts Institute of Technology where I learned chemical biology and studied protein-carbohydrate interactions. in Chemistry from UNC-CH in 2016 for my research working with Professor Erik Alexanian on developing new transition metal-catalyzed carbon-carbon bond-forming reactions for organic synthesis.
After undergraduate school, I did a year of service in Central African Republic before beginning graduate studies at University of North Carolina at Chapel Hill. in Chemistry in 2010 from Messiah College, a liberal arts college in Mechanicsburg, PA. I am originally from southeastern Pennsylvania and graduated with a B.S. University of North Carolina at Chapel Hill Assistant Professor Organic and Biochemistry Contact Information
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